Sunday 2 June 2019

Trial of metformin for non-small cell lung cancer

Initial results of NRG-LU001 indicate that, although the diabetes agent metformin was well-tolerated by patients, the agent has not clearly improved progression-free survival (PFS) or overall survival (OS) for trial participants with locally advanced non-small cell lung cancer (NSCLC). These results are based on local center reported outcomes. Trial participants will continue to be followed for changes in their status. The initial report of these results were presented at the American Society of Clinical Oncology (ASCO) Annual Meeting and the abstract was awarded a "Best of ASCO" designation.

* This article was originally published here

K-Athena: a performance portable magnetohydrodynamics code

Running large-scale simulations is a crucial aspect of modern scientific research, yet it often requires a vast amount of computational resources. As we approach the era of exascale computing, which will be marked by the introduction of highly performing supercomputers, researchers have been trying to develop new architectures and codes to meet the huge computational requirements of our times. An important property to consider when developing codes for the exascale computing era is performance portability, which prevents the repeated, non-trivial refactoring of a code for different architectures.

* This article was originally published here

Nicotine and caffeine withdrawal may lead to unnecessary suffering and testing in intensive care patients

Nicotine and caffeine withdrawal can cause unnecessary suffering to patients in intensive care units (ICUs), and could be leading to unneeded laboratory testing and diagnostic imaging such as X-rays and MRIs, according to a systematic review of clinical and observational studies involving 483 adults.

* This article was originally published here

Connected champagne putting a cork in bogus bubbly

Champagne is now connected: Thanks to tracking technology, champagne houses now have tools to better guard against fraud while gaining a new channel to interact with their customers.

* This article was originally published here

Men who choose active surveillance for early prostate cancer often don't follow monitoring rules

Preliminary results from a University of North Carolina Lineberger Comprehensive Cancer Center study found that just 15 percent of a group of men in North Carolina with early-stage prostate cancer who choose active surveillance instead of treatment followed the recommended monitoring guidelines.

* This article was originally published here